Monday, 22 October, 2018

Costs of daily aspirin may outweigh benefits for older adults, study finds

The report informs consuming Aspirin might also increase the risk of a potential internal bleeding The report informs consuming Aspirin might also increase the risk of a potential internal bleeding
Delia Stanley | 19 September, 2018, 20:39

In spite of the above results, researchers still say that if you are a healthy, elderly person and you have been taking aspirin daily, you shouldn't necessarily stop.

So yes, don't pop aspirin if you are healthy. As the blood vessel walls weaken, the risk of bleeding due to aspirin intake rises, he said.

"This study shows why it is so important to conduct this type of research, so that we can gain a fuller picture of aspirin's benefits and risks among healthy older persons", Richard Hodes, director of the National Institute of Ageing, which helped fund the trial, said in a statement.

Millions of healthy people who take aspirin to ward off illness in old age are unlikely to benefit from the drug, a trial has found.

According to the New England Journal of Medicine, regularly taking aspirin can actually be harmful.

This was one finding from our seven-year study that included more than 19,000 older people from Australia and the US.

Half of them were asked to take 100mg of aspirin a day, while the other half took a placebo.

The study also showed slightly higher rates of death in those taking aspirin, primarily from cancer, although the results were not statistically significant, he said.

McNeil added that a small increase in deaths observed in the aspirin group, primarily from cancer, required further investigation as researchers can not rule out that it may be a chance finding.

Taking low-dose aspirin daily doesn't preserve good health or delay the onset of disability or dementia in healthy older people.

There's a common belief a low dose of aspirin a day helps seniors live longer, but a new study has found it does nothing of the sort. Professor McNeil said disability-free survival measures "how long it took for people to remain healthy without having a permanent physical disability or developing dementia", or the time people spent in "healthy state".

The trial was supported by grants from the National Institute on Aging and the National Cancer Institute at the NIH; the National Health and Medical Research Council of Australia; Monash University; and the Victorian Cancer Agency. "But not only did it not decrease risk of disability or death, it did not decrease the risk of heart attack and stroke, and there was an increase in the rate of death". Yet, many healthy older people continued being prescribed aspirin for this goal. Caution was advised for this particular finding since the follow-up period (five years) may have limited the ability to observe benefits such as the reduced risk of colorectal cancer. You should rather ask your doctor for guidance on which steps you will need to take going forward.

In the second study, researchers were able to confirm these results, noting "the risk of major hemorrhage was significantly higher with aspirin than with a placebo". And 5.9% of those taking aspirin died during the study, compared to 5.2% of the placebo-takers.

"The rate of major hemorrhage was 8.6 events per 1000 person-years and 6.2 events per 1000 person-years, respectively (hazard ratio, 1.38; 95% CI, 1.18 to 1.62; P 0.001)". The age limit was lowered for those groups because blacks and Hispanics tend to be younger than whites when they have their first heart attack or stroke.

The current guidelines recommend a daily aspirin for adults in their 50s who are at high risk of cardiovascular disease, such as high blood pressure, high cholesterol or a history of smoking.

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